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Filtered Search Results
Medchemexpress LLC TNF-alpha/TNFSF2 Cy 100ug | 100ug
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Tumour Necrosis Factor alpha (TNF alpha) is a potent pro-inflammatory cytokine[1] TNF alpha binds to its receptors mainly TNFR1 and TNFR2 and then transmits molecular signals for biological functions such as inflammation and cell death[2] TNF alpha stimulates NF- B pathway via TNFR2 promotes cancer growth invasion and metastasis Anti-TNF- MAb significantly suppresses the tumor development in colitis-associated cancer (CAC) mouse[3] TNF alpha as a proneurogenic factor activates the SAPK/JNK Pathway and can facilitate neuronal replacement and brain repair in response to brain injury[4] TNF-alpha/TNFSF2 Protein Cynomolgus (Biotinylated) is a biotinylated recombinant protein consisting of 157 amino acids (V77-L233) and is produced in E coli
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Medchemexpress LLC Fumaric acid-13C4 | 201595-62-2 | MFCD00144377 | 98.0% | 120.04 | 13C4H4O4 | 1 MG
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Fumaric acid-13C4 is the 13C-labeled form of fumaric acid supplied for laboratory research. It is intended for use in stable-isotope metabolic tracing, mass spectrometry, and metabolic flux analysis, and is provided with supporting documentation (datasheet, SDS, COA).
- 98.0% purity.
- Molecular formula 13C4H4O4 and molecular weight 120.04.
- Suitable for stable-isotope metabolic tracing and mass spectrometry.
- Provided with datasheet, safety data sheet, and certificate of analysis.
- Available in small, pre-weighed quantities for tracer studies.
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Medchemexpress LLC Melinamide | 14417-88-0 | 99.9% | 383.61 g·mol-1 | C26H41NO | 25 MG
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Melinamide is an amide derivative of an unsaturated long-chain fatty acid used as a research tool to inhibit cholesterol absorption. It shows an IC50 of 20.9 μM for cholesterol uptake and inhibits acyl CoA:cholesterol acyltransferase (ACAT) activity in mucosal microsomes. For laboratory research use only.
- Purity 99.9%.
- CAS number 14417-88-0.
- Chemical formula C26H41NO.
- Molecular weight 383.61 g·mol-1.
- Activity IC50 20.9 μM for cholesterol absorption inhibition.
- Additional ACAT inhibition reported (50% inhibition at ~0.5 μM).
- Available as small-scale mg quantities and as a DMSO solution for research use.
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Medchemexpress LLC 4-Methyloctanoic acid | 54947-74-9 | 99.85% | 158.24 | 100 G
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4-Methyloctanoic acid is a natural compound primarily responsible for the characteristic "goaty" or "sheepy" flavor found in the milk of sheep and goats. It is intended for research use only and is not sold to patients.
- Purity: 99.85%
- Appearance: Liquid (density: 0.91 g/cm³)
- Color: Colorless to light yellow
- Initial source: Animals (sheep milk)
- Storage: Store at room temperature for 3 years; in solvent: -80°C for 2 years, -20°C for 1 year.
- Solubility (in vitro): 100 mg/mL in DMSO (631.95 mM); requires ultrasonic and freshly opened DMSO due to hygroscopic nature.
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Cayman Chemical 2-hexyl-4-PentynoIc AcId 1g
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Inhibits HDAC activity much more potently (IC50 = 13 µM) than valproic acid (IC50 = 398 µM); induces histone hyperacetylation in cerebellar granule cells significantly at 5 µM; induces the expression of Hsp70-1a and Hsp70-1b and protects cerebellar granule cells from glutamate-induced excitotoxicity
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Medchemexpress LLC HY-Y0366 1g Medchemexpress, Lauric acid CAS:143-07-7 Purity:>98%
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Medchemexpress, HY-Y0366 1g Lauric acid CAS:143-07-7 Lauric acid is a middle chain-free fatty acid with strong bactericidal properties. The EC 50 s for P. acnes, S.aureus, S. epidermidis, are 2, 6, 4 μg/mL, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC 4-Methyloctanoic acid | 54947-74-9 | 99.9% | 158.24 | 1 ML
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4-Methyloctanoic acid is a natural compound primarily responsible for the distinctive goaty and sheepy flavor found in milk from these animals.
- Natural compound
- Responsible for specific flavor profile
- Useful for research applications
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Medchemexpress LLC TNF-ALPHA/TNFSF2 CY 50UG
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5000186691 TNF-ALPHA/TNFSF2 CY 50UG
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Cayman Chemical 2-fluoro PalmItIc AcId 10mg
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2-fluoro Palmitic acid inhibits sphingosine biosynthesis and long-chain acyl-CoA synthetase with an IC50 value of 0.2 mM.{1613}
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Medchemexpress LLC Lignoceric acid | 557-59-5 | 98.0% | 100 MG
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Lignoceric acid (tetracosanoic acid) is a 24-carbon saturated (24:0) long-chain fatty acid supplied as a solid for laboratory use. It is used as a reagent and reference standard in lipid research and analytical chemistry.
- 24-carbon saturated fatty acid (C24:0).
- Molecular weight 368.64 g/mol; formula C24H48O2.
- High purity, listed as 98.0%.
- Available in small pack sizes suitable for analytical work, including 100 mg.
- Solid, white to off-white appearance.
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Cayman Chemical LIgnocerIc AcId 500mg
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A 24-carbon saturated (24:0) fatty acid that is synthesized during brain development and is found in cerebrosides
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eMolecules 203787-91-1 | Octanoic acid, 8-[(2-hydroxybenzoyl)amino]-, monosodium salt | Combi-Blocks, Inc. | MFCD00952954 | 301.318 | C15H20NNaO4 | 97.000 | [Na+].Oc1ccccc1C(=O)NCCCCCCCC([O-])=O | 100g | 642101825
Octanoic acid, 8-[(2-hydroxybenzoyl)amino]-, monosodium salt | Combi-Blocks, Inc. | 203787-91-1 | MFCD00952954 | 301.318 | C15H20NNaO4 | 97.000 | [Na+].Oc1ccccc1C(=O)NCCCCCCCC([O-])=O | 100g | 642101825
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Medchemexpress LLC L-Allylglycine | 16338-48-0 | MFCD00002627 | ≥98.0% | 115.13 | 25 G
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L-Allylglycine (L-2-Allylglycine) is an amino acid derivative that functions as an inhibitor for glutamate decarboxylase (GAD), thereby reducing GABA biosynthesis in the brain. It exhibits convulsant activity and is intended for research use only. Studies have shown that L-Allylglycine induces convulsive behaviors in Sprague-Dawley rat models, reducing GABA content in the hippocampus, cortex, and cerebellum, and inducing running fits, partial rigidity, and convulsions.
- Inhibits glutamate decarboxylase.
- Reduces GABA biosynthesis in the brain.
- Exhibits convulsant activity.
- Induces convulsive behaviors in rat models.
- Reduces GABA content in various brain regions.
- For research use only.
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Medchemexpress LLC Octanoic acid, 2-(2-propyn-1-yl)- | 96017-59-3 | MFCD00946863 | 98.0% | 182.26 g/mol | C11H18O2 | 10 MG
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2-Hexyl-4-pentynoic acid is an alkynyl-substituted octanoic acid used in biochemical and cell-based research as a histone deacetylase (HDAC) inhibitor. The compound contains a terminal alkyne for click-chemistry applications and is supplied as a colorless to light yellow liquid at high reported purity.
- Alkynyl-substituted octanoic acid with HDAC inhibitory activity.
- Terminal alkyne functional group suitable for copper-catalyzed azide-alkyne cycloaddition (click chemistry).
- High reported purity (98.0%) and supplied as a liquid.
- Small packaging options available, including 10 mg quantities for research use.
- CAS number 96017-59-3; molecular weight 182.26 g/mol.
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Medchemexpress LLC TNF-alpha/TNFSF2 Cy 100ug
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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TNF-alpha/TNFSF2 protein binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR It induces tumor cell death fever cachexia cell proliferation and cell differentiation It also causes insulin resistance and GKAP42 protein degradation in adipocytes Additionally it plays a role in angiogenesis osteoclastogenesis and IL12 production in dendritic cells TNF-alpha/TNFSF2 Protein Cynomolgus (N-His) is the recombinant cynomolgus-derived TNF-alpha/TNFSF2 protein expressed by E coli with N-6 His labeled tag
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